Wissenschaftliche Originalarbeiten
- Alsat EA, Reutter H, Bagci S, Kipfmueller F, Engels H, Raff R, Mangold E, Gembruch U, Geipel A, Müller A, Schaible T (2018) Congenital diaphragmatic hernia in a case of Cat eye syndrome. Clinical Case Reports 6:1786-1790. PMID: 30214764
- Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Yin D, Ellis G, Ben-Shoshan M, Marenholz I, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk R, Dubois AEJ, Grosche S, Ashley S, Rüschendorf F, Kalb B, Beyer K, Nöthen MM, Lee YA, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D (2018) A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma. Journal of Allergy and Clinical Immunology 141:1513-1516. PMID: 29325868
- Bagci S, Mensinga D, Katzer D, Merz WM, Reutter H, Müller A (2018) An examination of the factors affecting intestinal wall integrity in newborns at birth. Journal of Maternal-Fetal & Neonatal Medicine 31:294-299. PMID: 28110600
- Begemann M, Rezwan FI, Beygo J, Docherty LE, Kolarova J, Schroeder C, Buiting K, Chokkalingam K, Degenhardt F, Wakeling EL, Kleinle S, González Fassrainer D, Oehl-Jaschkowitz B, Turner CLS, Patalan M, Gizewska M, Binder G, Bich Ngoc CT, Chi Dung V, Mehta SG, Baynam G, Hamilton-Shield JP, Aljareh S, Lokulo-Sodipe O, Horton R, Siebert R, Elbracht M, Temple IK, Eggermann T, Mackay DJG (2018) Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring. Journal of Medical Genetics 55:497-504. PMID: 29574422
- Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Herms F, Hoffmann P, Nöthen MM, Reif A] (2018) Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173(7):1705-1715. PMID: 29906448
- Birtel J, Eisenberger T, Gliem M, Müller PL, Herrmann P, Betz C, Zahnleiter D, Neuhaus C, Lenzner S, Holz FG, Mangold E, Bolz HJ, Charbel Issa P (2018) Clinical and genetic characteristics of 251 consecutive patients with macular and cone/cone-rod dystrophy. Science Report 19;8(1):4824. doi: 10.1038/s41598-018-22096-0. PMID: 29555955
- Birtel J, Gliem M, Mangold E, Müller PL, Holz FG, Neuhaus C, Lenzner S, Zahnleiter D, Betz C, Eisenberger T, Bolz HJ, Charbel Issa P (2018) Next-generation sequencing identifies unexpected genotype-phenotype correlations in patients with retinitis pigmentosa. PLoS One 13(12):e0207958. doi: 10.1371/journal.pone.0207958. eCollection 2018.PMID: 30543658
- Böhmer AC, Gölz L, Kreusch T, Kramer FJ, Pötzsch B, Nöthen MM, Jäger A, Mangold E, Knapp M, Ludwig KU (2018) Investigation of dominant and recessive inheritance models in genome-wide association studies data of nonsyndromic cleft lip with or without cleft palate. Birth Defects Research 110:336-341. PMID: 29134786
- Bogs T, Zwink N, Chonitzki V, Hölscher A, Boemers TM, Münsterer O, Kurz R, Heydweiller A, Pauly M, Leutner A, Ure BM, Lacher M, Deffaa OJ, Thiele H, Bagci S, Jenetzky E, Schumacher J, Reutter H (2018) Esophageal atresia with or without tracheoesophageal fistula (EA/TEF): Association of different EA/TEF subtypes with specific co-occurring congenital anomalies and implications for diagnostic workup. European Journal of Pediatric Surgery 28:176-182. PMID: 28061520
- Božić T, Frobel J, Raic A, Ticconi F, Kuo CC, Heilmann-Heimbach S, Goecke TW, Zenke M, Jost E, Costa IG, Wagner W (2018) Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis. Life Science Alliance 1(6):e201800153. doi: 10.26508/lsa.201800153. PMID: 30582132
- Brainstorm Consortium [Nöthen MM, Hoffmann P, Herms S, Maaser A, Forstner AJ, Degenhardt F, Schumacher J] (2018) Analysis of shared heritability in common disorders of the brain. Science 360 (6395). pii: eaap8757. doi: 10.1126/science.aap8757. PMID: 29930110
- Bramswig NC, Bertoli-Avella AM, Albrecht B, Al Aqeel AI, Alhashem A, Al-Sannaa N, Bah M, Bröhl K, Depienne C, Dorison N, Doummar D, Ehmke N, Elbendary HM, Gorokhova S, Héron D, Horn D, James K, Keren B, Kuechler A, Ismail S, Issa MY, Marey I, Mayer M, McEvoy-Venneri J, Megarbane A, Mignot C, Mohamed S, Nava C, Philip N, Ravix C, Rolfs A, Sadek AA, Segebrecht L, Stanley V, Trautman C, Valence S, Villard L, Wieland T, Engels H, Strom TM, Zaki MS, Gleeson JG, Lüdecke HJ, Bauer P, Wieczorek D (2018) Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies). Human Genetics 137:753-768. PMID: 30167850
- Breuer R*, Mattheisen M*, Frank J, Krumm B, Treutlein J, Kassem L, Strohmaier J, Herms S, Mühleisen TW, Degenhardt F, Cichon S, Nöthen MM, Karypis G, Kelsoe J, Greenwood T, Nievergelt C, Shilling P, Shekhtman T, Edenberg H, Craig D, Szelinger S, Nurnberger J, Gershon E, Alliey-Rodriguez N, Zandi P, Goes F, Schork N, Smith E, Koller D, Zhang P, Badner J, Berrettini W, Bloss C, Byerley W, Coryell W, Foroud T, Guo Y, Hipolito M, Keating B, Lawson W, Liu C, Mahon P, McInnis M, Murray S, Nwulia E, Potash J, Rice J, Scheftner W, Zöllner S, McMahon FJ, Rietschel M, Schulze TG (2018) Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics. International Journal of Bipolar Disorders 6:24. doi: 10.1186/s40345-018-0132-x. PMID: 30415424 *These authors contributed equally to this work.
- Cao H, Harneit A, Walter H, Erk S, Braun U, Moessnang C, Geiger LS, Zang Z, Mohnke S, Heinz A, Romanczuk-Seiferth N, Mühleisen T, Mattheisen M, Witt SH, Cichon S, Nöthen MM, Rietschel M, Meyer-Lindenberg A, Tost H (2018) The 5-HTTLPR polymorphism affects network-based functional connectivity in the visual-limbic system in healthy adults. Neuropsychopharmacology 43:406-414. PMID: 28589968
- Casper M, Spier I, Holz R, Aretz S, Lammert F (2018) Phenotypic variability of MUTYH-associated polyposis in monozygotic twins and endoscopic resection of a giant polyp in pregnancy. American Journal of Gastroenterology 113:625-627. PMID: 29610499
- Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM; Swedish Bipolar Study Group; MooDS Bipolar Consortium, Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M (2018) The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Molecular Psychiatry 23:400-412. PMID: 28070120
- Chattopadhyay S, Thomsen H, da Silva Filho MI, Weinhold N, Hoffmann P, Nöthen MM, Marina A, Jöckel KH, Schmidt B, Pechlivanis S, Langer C, Goldschmidt H, Hemminki K, Försti A (2018) Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study. Molecular Medicine 24(1):30. doi: 10.1186/s10020-018-0031-8. PMID: 30134812
- Cheesman R, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Purves KL, Pingault JB, Breen G, Rijsdij K F, Plomin R, Eley TC (2018) Extracting stability increases the SNP heritability of emotional problems in young people. Translational Psychiatry 8:223. doi: 10.1038/s41398-018-0269-5. PMID: 30333497
- Chiocchetti AG, Yousaf A, Bour HS, Haslinger D, Waltes R, Duketis E, Jarczok T, Sachse M, Biscaldi M, Degenhardt F, Herms S, Cichon S, Ackermann J, Koch I, Klauck SM, Freitag CM (2018) Common functional variants of the glutamatergic system in autism spectrum disorder with high and low intellectual abilities. Journal of Neural Transmission (Vienna) 125:259-271. PMID: 29147782
- Claus EB, Cornish AJ, Broderick P, Schildkraut JM, Dobbins SE, Holroyd A, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Swerdlow A, Larsen SB, Johansen C, Simon M, Bondy M, Wrensch M, Houlston RS, Wiemels JL (2018) Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. Neuro-Oncology 20:1485-1493. PMID: 29762745
- Colodro-Conde L, Couvy-Duchesne B, Zhu G, Coventry WL, Byrne EM, Gordon S, Wright MJ, Montgomery GW, Madden PAF; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Ripke S, Eaves LJ, Heath AC, Wray NR, Medland SE, Martin NG (2018) A direct test of the diathesis-stress model for depression (2018) Molecular Psychiatry 23:1590-1596. PMID: 28696435
- Crawford B, Craig Z, Mansell G, White I, Smith A, Spaull S, Imm J, Hannon E, Wood A, Yaghootkar H, Ji YJ, Major Depressive Disorder Working[Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Mullins N, Lewis CM, Mill J, Murphy TM (2018) DNA methylation and inflammation marker profiles associated with a history of depression. Human Molecular Genetics 27: 2840-2850
- Czauderna C, Palestino-Dominguez M, Castven D, Becker D, Zanon-Rodriguez L, Hajduk J, Mahn FL, Herr M, Strand D, Strand S, Heilmann-Heimbach S, Gomez-Quiroz LE, Wörns MA, Galle PR, Marquardt JU (2018) Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver. PLoS One 13(12):e0209067. doi: 10.1371/journal.pone.0209067. PMID: 30576355
- Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, …, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, …, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ (2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications 9(1):2098. doi: 10.1038/s41467-018-04362-x. PMID: 29844566
- de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G (2018) Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology 1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018. PMID: 30320231
- Disney-Hogg L, Cornish AJ, Sud A, Law PJ, Kinnersley B, Jacobs DI, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il’yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS (2018) Impact of atopy on risk of glioma: a Mendelian randomisation study. BMC Medicine 16(1):42. doi: 10.1186/s12916-018-1027-5. PMID: 29540232
- Disney-Hogg L, Sud A, Law PJ, Cornish AJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il’yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Swerdlow AJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS (2018) Influence of obesity-related risk factors in the aetiology of glioma. British Journal of Cancer 118:1020-1027. PMID: 29531326
- Dworschak GC, Engels H, Becker J, Soellner L, Eggermann T, Kipfmueller F, Müller A, Reutter H, Kreiß M (2018) De novo duplication of 11p15 associated with congenital diaphragmatic hernia. Frontiers in Pediatrics 6:116. doi: 10.3389/fped.2018.00116. eCollection 2018. PMID: 29922638
- Ebert AK, Zwink N, Schwarzer N, Brunner L, Reutter H, Jenetzky E, Huber J, Ludwikowski B (2018) Needs assessment in care of adults with anorectal malformations and exstrophy-epispadias complex in Germany. Frontiers in Pediatrics 6:392. doi: 10.3389/fped.2018.00392. eCollection 2018. PMID: 30619788
- Engel C, Vasen HF, Seppälä T, Aretz S, Bigirwamungu-Bargeman M, de Boer SY, Bucksch K, Büttner R, Holinski-Feder E, Holzapfel S, Hüneburg R, Jacobs MAJM, Järvinen H, Kloor M, von Knebel Doeberitz M, Koornstra JJ, van Kouwen M, Langers AM, van de Meeberg PC, Morak M, Möslein G, Nagengast FM, Pylvänäinen K, Rahner N, Renkonen-Sinisalo L, Sanduleanu S, Schackert HK, Schmiegel W, Schulmann K, Steinke-Lange V, Strassburg CP, Vecht J, Verhulst ML, de Vos Tot Nederveen Cappel W, Zachariae S, Mecklin JP, Loeffler M; German HNPCC Consortium, the Dutch Lynch Syndrome Collaborative Group, and the Finnish Lynch Syndrome Registry (2018) No difference in colorectal cancer incidence or stage at detection by colonoscopy among 3 countries with different Lynch syndrome surveillance policies. Gastroenterology 155:1400-1409. PMID: 30063918
- Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, Marquié M, Santos-Santos MA, Sanabria Á, Ortega G, Monté-Rubio G, Pérez A, Ibarria M, Ruiz S, Kornhuber J, Peters O, Frölich L, Hüll M, Wiltfang J, Luck T, Riedel-Heller S, Montrreal L, Cañabate P, Moreno M, Preckler S, Aguilera N, de Rojas I, Orellana A, Alegret M, Valero S, Nöthen MM, Wagner M, Jessen F, Tárraga L, Boada M, Ramírez A, Ruiz A (2018) Exploring genetic associations of Alzheimer’s disease loci with mild cognitive impairment neurocognitive endophenotypes. Frontiers in Aging Neuroscience 10:340. doi: 10.3389/fnagi.2018.00340. eCollection 2018. PMID: 30425636
- Fernandez-Rebollo E, Eipel M, Seefried L, Hoffmann P, Strathmann K, Jakob F, Wagner W (2018) Primary osteoporosis is not reflected by disease-specific DNA methylation or accelerated epigenetic age in blood. Journal of Bone and Mineral Research 33:356-361. PMID: 28926142
- Foo JC, Streit F, Treutlein J, Ripke S, Witt SH, Strohmaier J, Degenhardt F, Forstner AJ, Hoffmann P, Soyka M, Dahmen N, Scherbaum N, Wodarz N, Heilmann-Heimbach S, Herms S, Cichon S, Preuss U, Gaebel W, Ridinger M, Hoffmann S, Schulze TG, Maier W, Zill P, Müller-Myhsok B, Ising M, Lucae S, Nöthen MM, Mann K, Kiefer F, Rietschel M, Frank J; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM] (2018) Shared genetic etiology between alcohol dependence and major depressive disorder. Psychiatric Genetics 28:66-70. PMID: 29901528
- Frank J, Ralser DJ, Betz RC (2018) Intra- and interfamilial phenotype variability associated with mutations in γ-secretase subunit-encoding PSENEN. Journal of Investigative Dermatology 138:1215-1218. PMID: 29138052
- Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M (2018) Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease. Brain 141:1186-1200. PMID: 29462334
- Freytag V, Vukojevic V, Wagner-Thelen H, Milnik A, Vogler C, Leber M, Weinhold L, Böhmer AC, Riedel-Heller S, Maier W, de Quervain DJ, Ramirez A, Papassotiropoulos A (2018) Genetic estimators of DNA methylation provide insights into the molecular basis of polygenic traits. Translational Psychiatry 2018 Jan 31;8(1):31. doi: 10.1038/s41398-017-0070-x. PMID: 29382824
- Fritzen D*, Kuechler A*, Grimmel M*, Becker J, Peters S, Sturm M, Hundertmark H, Schmidt A, Kreiß M, Strom TM, Wieczorek D, Haack TB, Beck-Wödl S, Cremer K**, Engels H** (2018) De novo FBXO11 mutations are associated with intellectual disability and behavioural anomalies. Human Genetics 137:401-411. PMID: 29796876. *These authors contributed equally to this work. **These authors contributed equally to this work.
- Gatzweiler E, Hoppe B, Dewald O, Berg C, Müller A, Reutter H, Kipfmueller F (2018) Extracorporeal membrane oxygenation support in a newborn with lower urinary tract obstruction and pulmonary hypoplasia: a case report. Journal of Medical Case Reports 12(1):210. doi: 10.1186/s13256-018-1749-1. PMID: 30012211
- Guzman-Parra J, Rivas F, Strohmaier J, Forstner A, Streit F, Auburger G, Propping P, Orozco-Diaz G, González MJ, Gil-Flores S, Cabaleiro-Fabeiro FJ, Del Río-Noriega F, Perez-Perez F, Haro-González J, de Diego-Otero Y, Romero-Sanchiz P, Moreno-Küstner B, Cichon S, Nöthen MM, Rietschel M, Mayoral F (2018) The Andalusian bipolar family (ABiF) study: Protocol and sample description. Revista de Psiquiatría y Salud Mental 11:199-207. PMID: 28619597
- Haenisch B, Molderings GJ (2018) White matter abnormalities are also repeatedly present in patients with systemic mast cell activation syndrome. Translational Psychiatry 8:95. doi: 10.1038/s41398-018-0143-5. PMID: 29743606
- Hall LS, Adams MJ, Arnau-Soler A, Clarke TK, Howard DM, Zeng Y, Davies G, Hagenaars SP, Maria Fernandez-Pujals A, Gibson J, Wigmore EM, Boutin TS, Hayward C, Scotland G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Porteous DJ, Deary IJ, Thomson PA, Haley CS, McIntosh AM (2018) Genome-wide meta-analyses of stratified depression in generation Scotland and UK biobank. Translational Psychiatry 8:9. doi: 10.1038/s41398-017-0034-1. PMID: 29317602
- Heinrichs SKM, Hess T, Becker J, Hamann L, Vashist YK, Butterbach K, Schmidt T, Alakus H, Krasniuk I, Höblinger A, Lingohr P, Ludwig M, Hagel AF, Schildberg CW, Veits L, Gyvyte U, Weise K, Schüller V, Böhmer AC, Schröder J, Gehlen J, Kreuser N, Hofer S, Lang H, Lordick F, Malfertheiner P, Moehler M, Pech O, Vassos N, Rodermann E, Izbicki JR, Kruschewski M, Ott K, Schumann RR, Vieth M, Mangold E, Gasenko E, Kupcinskas L, Brenner H, Grimminger P, Bujanda L, Sopeña F, Espinel J, Thomson C, Pérez-Aísa Á, Campo R, Geijo F, Collette D, Bruns C, Messerle K, Gockel I, Nöthen MM, Lippert H, Ridwelski K, Lanas A, Keller G, Knapp M, Leja M, Kupcinskas J, García-González MA, Venerito M, Schumacher J (2018) Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. Cancer Medicine 7:5057-5065. PMID: 30191681
- Hench J, Bihl M, Bratic Hench I, Hoffmann P, Tolnay M, Bösch Al Jadooa N, Mariani L, Capper D, Frank S (2018) Satisfying your neuro-oncologist: a fast approach to routine molecular glioma diagnostics. Neuro-Oncology 20:1682-1683. PMID: 30169880
- Herrera-Rivero M, Zhang R, Heilmann-Heimbach S, Mueller A, Bagci S, Dresbach T, Schröder L, Holdenrieder S, Reutter HM, Kipfmueller F (2018) Circulating microRNAs are associated with pulmonary hypertension and development of chronic lung disease in congenital diaphragmatic hernia. Scientific Reports 8(1):10735. doi: 10.1038/s41598-018-29153-8. PMID: 30013141
- Howe LJ, Lee MK, Sharp GC, Davey Smith G, St Pourcain B, Shaffer JR, Ludwig KU, Mangold E, Marazita ML, Feingold E, Zhurov A, Stergiakouli E, Sandy J, Richmond S, Weinberg SM, Hemani G, Lewis SJ (2018) Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology. PLoS Genetics 14:e1007501. doi: 10.1371/journal.pgen.1007501. eCollection 2018 Aug. PMID: 30067744
- Huckins LM, Hatzikotoulas K, Southam L, Thornton LM, Steinberg J, Aguilera-McKay F, Treasure J, Schmidt U, Gunasinghe C, Romero A, Curtis C, Rhodes D, Moens J, Kalsi G, Dempster D, Leung R, Keohane A, Burghardt R, Ehrlich S, Hebebrand J, Hinney A, Ludolph A, Walton E, Deloukas P, Hofman A, Palotie A, Palta P, van Rooij FJA, Stirrups K, Adan R, Boni C, Cone R, Dedoussis G, van Furth E, Gonidakis F, Gorwood P, Hudson J, Kaprio J, Kas M, Keski-Rahonen A, Kiezebrink K, Knudsen GP, Slof-Op ‚t Landt MCT, Maj M, Monteleone AM, Monteleone P, Raevuori AH, Reichborn-Kjennerud T, Tozzi F, Tsitsika A, van Elburg A; Eating Disorder Working Group of the Psychiatric Genomics Consortium [Cichon S], Collier DA, Sullivan PF, Breen G, Bulik CM, Zeggini E (2018) Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry 23:1169-1180. Erratum in: Mol Psychiatry. 2018 Sep;23(9):1. PMID: 29155802
- Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S (2018) Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. Translational Psychiatry 2018 Oct 8;8(1):210. doi: 10.1038/s41398-018-0175-x. PMID: 30297702
- Humbatova A, Maroofian R, Romano MT, Tafazzoli A, Behnam M, Dilaver N, Nouri N, Salehi M, Wolf S, Frank J, Kokordelis P, Betz RC (2018) An insertion mutation in HOXC13 underlies pure hair and nail ectodermal dysplasia with lacrimal duct obstruction. British Journal of Dermatology 178:e265-e267. PMID: 29278420
- International Consortium on Lithium Genetics (ConLi+Gen), Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A , Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O’Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Volkert J, Witt S, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT (2018) Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: a genome-wide association study. JAMA Psychiatry 75:65-74. PMID: 29121268
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- Navrady LB, Adams MJ, Chan SWY; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Ritchie SJ, McIntosh AM (2018) Genetic risk of major depressive disorder: the moderating and mediating effects of neuroticism and psychological resilience on clinical and self-reported depression. Psychological Medicine 48:1890-1899. PMID: 29183409
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- Palladino VS, Subrata NOC, Geburtig-Chiocchetti A, McNeill R, Hoffmann P, Reif A, Kittel-Schneider S (2018) Generation of human induced pluripotent stem cell lines (hiPSC) from one bipolar disorder patient carrier of a DGKH risk haplotype and one non-risk-variant-carrier bipolar disorder patient. Stem Cell Research 32:104-109. PMID: 30266033
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- Peloso GM, van der Lee SJ; International Genomics of Alzheimer’s Project (IGAP) [Heilmann-Heimbach S, Hoffmann, P, Nöthen MM, Forstner AJ], Destefano AL, Seshardi S (2018) Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer’s disease. Alzheimer’s & Dementia 10:595-598. PMID: 30422133
- Piel JH, Lett TA, Wackerhagen C, Plichta MM, Mohnke S, Grimm O, Romanczuk-Seiferth N, Degenhardt F, Tost H, Witt S, Nöthen M, Rietschel M, Heinz A, Meyer-Lindenberg A, Walter H, Erk S. (2018) The effect of 5-HTTLPR and a serotonergic multi-marker score on amygdala, prefrontal and anterior cingulate cortex reactivity and habituation in a large, healthy fMRI cohort. European Neuropsychopharmacology 28:415-427. PMID: 2935809
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- Reijnders MRF, Miller KA, Alvi M, Goos JAC, Lees MM, de Burca A, Henderson A, Kraus A, Mikat B, de Vries BBA, Isidor B, Kerr B, Marcelis C, Schluth-Bolard C, Deshpande C, Ruivenkamp CAL, Wieczorek D; Deciphering Developmental Disorders Study, Baralle D, Blair EM, Engels H, Lüdecke HJ, Eason J, Santen GWE, Clayton-Smith J, Chandler K, Tatton-Brown K, Payne K, Helbig K, Radtke K, Nugent KM, Cremer K, Strom TM, Bird LM, Sinnema M, Bitner-Glindzicz M, van Dooren MF, Alders M, Koopmans M, Brick L, Kozenko M, Harline ML, Klaassens M, Steinraths M, Cooper NS, Edery P, Yap P, Terhal PA, van der Spek PJ, Lakeman P, Taylor RL, Littlejohn RO, Pfundt R, Mercimek-Andrews S, Stegmann APA, Kant SG, McLean S, Joss S, Swagemakers SMA, Douzgou S, Wall SA, Küry S, Calpena E, Koelling N, McGowan SJ, Twigg SRF, Mathijssen IMJ, Nellaker C, Brunner HG, Wilkie AOM (2018) De novo and inherited loss-of-function variants in TLK2: clinical and genotype-phenotype evaluation of a distinct neurodevelopmental disorder. American Journal of Human Genetics 102:1195-1203. PMID: 29861108
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- Romano MT, Tafazzoli A, Mattern M, Sivalingam S, Wolf S, Rupp A, Thiele H, Altmüller J, Nürnberg P, Ellwanger J, Gambon R, Baumer A, Kohlschmidt N, Metze D, Holdenrieder S, Paus R, Lütjohann D, Frank J, Geyer M, Bertolini M, Kokordelis P, Betz RC (2018) Bi-allelic mutations in LSS, encoding lanosterol synthase, cause autosomal-recessive hypotrichosis simplex. American Journal of Human Genetics 103:777-785. PMID: 30401459
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- Streit F, Treutlein J, Frischknecht U, Hermann D, Mann K, Kiefer F, Sack M, Hall ASM, Frank J, Witt SH, Foo JC, Degenhardt F, Heilmann-Heimbach S, Nöthen MM, Sommer WH, Spanagel R, Rietschel M, Ende G (2018) Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes. Psychiatric Genetics 28:94-95. PMID: 29985185
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